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We are offering to sell Resveratrol-Grape Skin Extract 50%90%98%.
Cancer-Related Effects
Resveratrol is being studied to see how it affects the initiation, promotion, and progression of cancer. With regard to tumor initiation, it has been shown to act as an antioxidant by inhibiting free radical formation, and as an anti-mutagen in rat models. Resveratrol appears to decrease tumor promotion activity by inhibiting cyclooxygenase-1 (COX-1), an enzyme that converts arachidonic acid to pro-inflammatory substances that stimulate tumor-cell growth . Studies related to progression have found that resveratrol induced human promyelocytic leukemia cell differentiation and inhibited ribonucleotide reductase, an enzyme needed for DNA synthesis in proliferating cells . One appealing characteristic of resveratrol's anti-cancer potential is its minimal toxicity to blood-forming cells . More studies using both cellular and animal models are needed before any such data would be applicable to human use.
The similarity in structure between resveratrol and diethylstilbestrol (a synthetic estrogen) has prompted investigations into resveratrol's potential as a phytoestrogen (a plant compound that produces estrogen-like effects). However, these properties also stimulate the growth of human breast cancer cells . This finding seems contrary to its other anticancer activities, and is a cause for concern.
The Natural Products Association was cited in an article regarding a new dietary supplement that contains resveratrol, a substance researchers believe may help protect human cells from diseases such as cancer and arthritis.
Direct Antioxidant Activity
In the test tube, resveratrol effectively scavenges (neutralizes) free radicals and other oxidants and inhibits low density lipoprotein (LDL) oxidation . However, there is little evidence that resveratrol is an important antioxidant in vivo . After oral consumption of resveratrol, circulating and intracellular levels of resveratrol in humans are likely to be much lower than that of other important antioxidants, such as vitamin C, vitamin E and glutathione. Moreover, the antioxidant activity of resveratrol metabolites, which comprise most of the circulating resveratrol, may be lower than that of
From: Changsha Organic Herb Inc
Posted on: 7/28/2008 1:24:15 AM
Expiring On: 1/24/2009 1:24:15 AM
Days Left: (53 days to go!)
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| Description |
We are offering to sell Resveratrol-Grape Skin Extract 50%90%98%.
Cancer-Related Effects
Resveratrol is being studied to see how it affects the initiation, promotion, and progression of cancer. With regard to tumor initiation, it has been shown to act as an antioxidant by inhibiting free radical formation, and as an anti-mutagen in rat models. Resveratrol appears to decrease tumor promotion activity by inhibiting cyclooxygenase-1 (COX-1), an enzyme that converts arachidonic acid to pro-inflammatory substances that stimulate tumor-cell growth . Studies related to progression have found that resveratrol induced human promyelocytic leukemia cell differentiation and inhibited ribonucleotide reductase, an enzyme needed for DNA synthesis in proliferating cells . One appealing characteristic of resveratrol's anti-cancer potential is its minimal toxicity to blood-forming cells . More studies using both cellular and animal models are needed before any such data would be applicable to human use.
The similarity in structure between resveratrol and diethylstilbestrol (a synthetic estrogen) has prompted investigations into resveratrol's potential as a phytoestrogen (a plant compound that produces estrogen-like effects). However, these properties also stimulate the growth of human breast cancer cells . This finding seems contrary to its other anticancer activities, and is a cause for concern.
The Natural Products Association was cited in an article regarding a new dietary supplement that contains resveratrol, a substance researchers believe may help protect human cells from diseases such as cancer and arthritis.
Direct Antioxidant Activity
In the test tube, resveratrol effectively scavenges (neutralizes) free radicals and other oxidants and inhibits low density lipoprotein (LDL) oxidation . However, there is little evidence that resveratrol is an important antioxidant in vivo . After oral consumption of resveratrol, circulating and intracellular levels of resveratrol in humans are likely to be much lower than that of other important antioxidants, such as vitamin C, vitamin E and glutathione. Moreover, the antioxidant activity of resveratrol metabolites, which comprise most of the circulating resveratrol, may be lower than that of |
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